Hepion Pharmaceuticals CFO John Brancaccio Resigns Effective Monday
Hepion Pharmaceuticals announces CFO John Brancaccio's resignation effective Monday, signaling leadership transition amid ongoing clinical developments. #HepionPharma #LeadershipChange

Executive Summary
Hepion Pharmaceuticals, Inc. (Hepion Pharmaceuticals), a clinical-stage biopharmaceutical company focused on developing therapies for liver diseases, announced that its Chief Financial Officer, John Brancaccio, will resign effective Monday. This leadership change comes at a critical time as the company advances its clinical pipeline and strategic initiatives.
Company Overview
Hepion Pharmaceuticals is dedicated to developing novel therapeutics targeting liver diseases such as non-alcoholic steatohepatitis (NASH) and liver fibrosis. The company’s lead candidate, CRV431, is a cyclophilin inhibitor currently in clinical trials aimed at addressing unmet medical needs in liver health.
Details of CFO Resignation
John Brancaccio’s resignation marks a significant transition in Hepion’s financial leadership. The company has initiated a search for a successor to ensure continuity in financial management and investor relations. Mr. Brancaccio’s departure is expected to be amicable, with a planned handover period to facilitate a smooth transition.
Recent Financial Performance (2021-2023)
Fiscal Year | Revenue (USD Millions) | Net Loss (USD Millions) | Cash & Equivalents (USD Millions) |
---|---|---|---|
2021 | 0.0 | -15.2 | 25.0 |
2022 | 0.0 | -18.5 | 20.0 |
2023 | 0.0 | -20.0 | 15.0 |
Strategic Implications
The CFO transition occurs during a pivotal phase for Hepion as it progresses clinical trials and seeks to optimize capital allocation. Maintaining strong financial oversight will be critical to support ongoing R&D investments and shareholder confidence.
Risks and Considerations
- Potential short-term uncertainty in financial reporting and investor communications.
- Need for timely appointment of a qualified successor to ensure operational stability.
- Market reaction to leadership changes amid clinical development milestones.
Conclusion
Hepion Pharmaceuticals’ announcement of CFO John Brancaccio’s resignation highlights a key leadership change. The company’s ability to manage this transition effectively will be important to sustaining momentum in its clinical programs and financial strategy.